/Dynorphin, Analogs and Sequences (38)
/Acetyl-(D-Lys2,Sar3)-Melanotropin-Potentiating Factor acetate salt
產品詳情
Cat#：136P35
序列（三字母）：Ac-Lys-D-Lys-Sar-Glu-OH acetate salt
序列（單字母）：Ac-Kk-Sar-E
類似名：Acetyl-(D-Lys??,Sar??)-β-Lipotropin (88-91) (human), Acetyl-(D-Lys2?,Sar3?)-β-Endorphin (28-31) (human)
分子式：C??H??N?O?
分子量：516.6
CAS#：81483-91-2
合成方法：Synthetic
存儲條件：-20 ± 5 °C
應用：Parkinson’s Disease
描述：This metabolically stable analog of MPF is known as a neurotrophic peptide capable of CNS regeneration. It has been shown to reduce parkinsonian-like behaviour in rats with unilateral lesions of their nigro-striatal pathways. This effect is related to reversal of the mitochondrial damage to the neurons. As a mitochondrial defect is supposed to be the initial step in the genesis of Parkinson′s disease, the peptide may be a very useful tool in the investigation of this disease.
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